Tepotinib in drug dose structure can be undaunted utilizing a straightforward, exact, precise, delicate, and explicit RP-HPLC approach. Chromatograph was gone through BDS C18 (4.8mm x 15cm, 5µm). Portable stage containing 0.1% TFA (CF3CO2H): MeOh taken in the proportion 55:45 was siphoned through section at a stream pace of 1.0ml/min. 30°C. λ max-310.0nm. The matter component eluted at 3.062 min. SST was passed accordingly_1.4%. Recovery is 0.9%. LOD, LOQ values got from R2 = 0.18, 0.55, R2 of Tepotinib is 41046x + 3649.6.