ABSTRACT: Floating Tablets of Lovastatin are formulated to increase gastric residence time and thereby improve its therapeutic efficacy. Eudragit RS 100 was respectively showed better Sustained drug release of Lovastatin. When drug: polymer concentration increases the release rate decreases this is because of reason when the concentration of polymer increases the diffusion path length increases. Formulated tablets showed satisfactory results for various Post compression evaluation parameters like: tablet thickness, hardness, weight variation, floating lag time, total floating time, content uniformity and in vitro drug release. Formulation F2 gave better-controlled drug release and floating properties in comparison to the other formulations. The release pattern of the F2 formulations was best fitted to Korsmeyer-Peppas model, Higuchi and first-order model. The most probable mechanism for the drug release pattern from the formulation was non-Fickian diffusion or anomalous diffusion.