Johncy Caroline.J
The present work is to devise a simple and convenient route to synthesis 2- amino -4-phenyl-4H-pyrano[3,2-h]quinoline-3-carboxylic acid ethyl esters by treatment of 8-hydroxyquinoline with aromatic aldehyde and ethyl cyano acetate using InCl3 as a catalyst. The synthesized heterocyclic compounds exhibited promising biological activities. Therefore, considerable effects have been directed towards the preparation and synthetic manipulation of this molecules .As a result ,a number of compounds have been obtained with diverse biological activities are synthesised
biological activities, quinoline derivatives